Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502516 | 0.86 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL7916768 | 0.84 | KDM4E (0.38) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL16502515 | 0.81 | NQO2 (0.42) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL7910683 | 0.78 | HTR5A (0.47) | — | |
| SCHEMBL7920129 | 0.73 | TNF (0.45) | MEN1KMT2ACYP1A2CYP2C19KDM4E | |
| SCHEMBL7916763 | 0.72 | RAB9A (0.35) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL16503550 | 0.71 | KDM4E (0.36) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL16502518 | 0.70 | PLA2G2D (0.44) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL7916817 | 0.70 | AKR1C3 (0.41) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL7918345 | 0.70 | CYP1A2 (0.40) | MEN1KMT2ACYP2A6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |