Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922096 | 0.93 | L3MBTL1 (0.49) | L3MBTL1MAPTRAB9AATMSMN1; SMN2 | |
| SCHEMBL7922037 | 0.89 | L3MBTL1 (0.45) | L3MBTL1MAPTRAB9AATMSMN1; SMN2 | |
| SCHEMBL7934182 | 0.84 | MAPT (0.46) | L3MBTL1MAPTRAB9AATMSMN1; SMN2 | |
| SCHEMBL7931127 | 0.82 | L3MBTL1 (0.48) | L3MBTL1MAPTRAB9AATMSMN1; SMN2 | |
| SCHEMBL6344107 | 0.81 | L3MBTL1 (0.47) | L3MBTL1MAPTRAB9AATMSMN1; SMN2 | |
| SCHEMBL7969081 | 0.78 | NCF1 (0.40) | L3MBTL1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL6352411 | 0.77 | ALDH1A1 (0.43) | MAPTSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL7922023 | 0.76 | NCF1 (0.38) | L3MBTL1MAPTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7931735 | 0.76 | L3MBTL1 (0.44) | L3MBTL1MAPTRAB9AATMALDH1A1 | |
| SCHEMBL7922045 | 0.75 | L3MBTL1 (0.40) | L3MBTL1KMT2ATDP1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140896-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| WO-2000037455-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-06-29 | — | — | WO | disclosed |