Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444252 | 0.76 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8839825 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5303417 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9476134 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11981966 | 0.69 | — | — | |
| SCHEMBL13639140 | 0.69 | — | — | |
| SCHEMBL2444823 | 0.68 | UGT2B7 (0.31) | — | |
| SCHEMBL3871232 | 0.68 | ALDH1A1 (0.44) | ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4266015 | 0.67 | ALDH1A1 (0.52) | ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12298894 | 0.67 | CA2 (0.33) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235780-B1 | ANTIHISTAMINE; VISION DEFECTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0974580-A1 | Omega-cycloalkyl-prostaglandin E1 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-26 | — | — | EP | disclosed |