Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14254562 | 0.80 | SMN1; SMN2 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL575895 | 0.70 | ALDH1A1 (0.64) | ALDH1A1MAPK1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL4179998 | 0.70 | ALDH1A1 (0.64) | ALDH1A1MAPK1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL420011 | 0.70 | ALDH1A1 (0.78) | ALDH1A1MAPK1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL1931125 | 0.70 | ALDH1A1 (0.78) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL19133464 | 0.69 | ALDH1A1 (0.61) | ALDH1A1MAPK1KDM4ECYP1A2CYP2D6 | |
| Fluoride SCHEMBL943089 | 0.69 | ALDH1A1 (0.61) | ALDH1A1MAPK1KDM4ECYP1A2CYP2D6 | |
| Fluoride SCHEMBL27793289 | 0.69 | ALDH1A1 (0.61) | ALDH1A1MAPK1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL2860864 | 0.69 | ALDH1A1 (0.61) | ALDH1A1MAPK1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL3868306 | 0.69 | PSIP1 (0.46) | ALDH1A1CYP2C19MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563924-B2 | 9-chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2009-07-21 | — | — | US | disclosed |
| US-7563924-B2 | 9-chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2009-07-21 | — | — | US | disclosed |
| US-7563924-B2 | 9-chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2009-07-21 | — | — | US | disclosed |
| EP-1816121-B1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | BAYER SCHERING PHARMA AG (DE) | 2008-03-12 | — | — | EP | disclosed |
| EP-1816121-B1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | BAYER SCHERING PHARMA AG (DE) | 2008-03-12 | — | — | EP | disclosed |
| US-20070203096-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-08-30 | — | — | US | disclosed |
| US-20070203096-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-08-30 | — | — | US | disclosed |
| US-20070203096-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-08-30 | — | — | US | disclosed |
| EP-1816121-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1816121-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-08-08 | — | — | EP | disclosed |
| WO-2007057232-A1 | 9-CHLORO-15-DEOXYPROSTAGLANDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007057232-A1 | 9-CHLORO-15-DEOXYPROSTAGLANDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203096-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | PGF, PTGIS, CYP11B2 | ALDH1A1 697/4885MAPK1 2520/4885KDM4E 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.