Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922085 | 0.87 | RAB9A (0.49) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL5228689 | 0.82 | RAB9A (0.61) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL29447082 | 0.82 | RAB9A (0.61) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL14806553 | 0.78 | L3MBTL1 (0.49) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL11116315 | 0.77 | L3MBTL1 (0.59) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL31731398 | 0.77 | RAB9A (0.49) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL12778688 | 0.77 | RAB9A (0.49) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL19756735 | 0.77 | RAB9A (0.49) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL9202106 | 0.76 | RAB9A (0.59) | L3MBTL1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL6629605 | 0.76 | RAB9A (0.54) | L3MBTL1GAARAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140896-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| WO-2000037455-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-06-29 | — | — | WO | disclosed |