Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209692 | 0.81 | MAPT (0.41) | CYP3A4HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8894104 | 0.81 | CA1 (0.32) | ALDH1A1 | |
| SCHEMBL17221770 | 0.80 | MGLL (0.41) | TSHR | |
| SCHEMBL9417699 | 0.78 | — | — | |
| SCHEMBL1773215 | 0.70 | ESR1 (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL4063477 | 0.69 | ESR1 (0.80) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL22335854 | 0.69 | ESR1 (0.80) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL18750 | 0.69 | ESR1 (0.80) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL28132199 | 0.69 | ESR1 (0.54) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL10708021 | 0.67 | ESR1 (0.52) | ESR1ESR2CYP3A4LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232430-B1 | PYRROLIDIN-2,5-DIONE COMPOUND | JDS UNIPHASE PHOTONICS C.V. (NL) | 2001-05-15 | — | — | US | disclosed |
| EP-0934266-A1 | CROSS-LINKERS FOR CROSS-LINKABLE OPTICAL POLYCARBONATES | Akzo Nobel N.V. (NL) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017644-A1 | CROSS-LINKERS FOR CROSS-LINKABLE OPTICAL POLYCARBONATES | AKZO NOBEL N.V. (NL) | 1998-04-30 | — | — | WO | disclosed |