Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 4/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 5/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920547 | 0.84 | MEN1 (0.38) | GHSRDPP8DPP9PRMT5WDR77 | |
| SCHEMBL7918007 | 0.84 | MEN1 (0.38) | GHSRDPP8DPP9PRMT5WDR77 | |
| SCHEMBL7917719 | 0.76 | GHSR (0.42) | GHSRDPP8DPP9P2RX7EPHX2 | |
| SCHEMBL7923515 | 0.76 | GHSR (0.42) | GHSRDPP8DPP9DRD2 | |
| SCHEMBL7917374 | 0.75 | GHSR (0.42) | GHSRDPP8DPP9P2RX7EPHX2 | |
| SCHEMBL12203923 | 0.75 | MEN1 (0.36) | GHSRDPP8DPP9PRMT5WDR77 | |
| SCHEMBL7930810 | 0.71 | DRD2 (0.46) | GHSRDRD2 | |
| SCHEMBL7924669 | 0.71 | GHSR (0.41) | GHSRDPP8DPP9PPIA | |
| SCHEMBL7918411 | 0.71 | GHSR (0.41) | GHSRDPP8DPP9PPIADRD2 | |
| SCHEMBL24437614 | 0.70 | TDP1 (0.36) | GHSRDPP8DPP9P2RX7PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |