Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919465 | 0.85 | ALDH1A1 (0.43) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL7922360 | 0.81 | MAOB (0.45) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL10238964 | 0.73 | LMNA (0.39) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL1391156 | 0.73 | USP14 (0.35) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL10239176 | 0.72 | PIM1 (0.32) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL1390757 | 0.68 | ALDH1A1 (0.43) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL10239177 | 0.68 | ALDH1A1 (0.42) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL22549667 | 0.65 | MAOB (0.40) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL1390653 | 0.65 | MAOB (0.45) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL10239175 | 0.64 | MAOB (0.44) | NPC1RAB9AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |