Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 3/20 | 0.38 |
| ▸ | ARG2 | P78540 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL1130394 | 0.89 | GSR (0.71) | GSRNOD1FOLH1SLC6A5ARG1 | |
| Lysine SCHEMBL9556358 | 0.89 | GSR (0.71) | GSRNOD1FOLH1SLC6A5ARG1 | |
| Ornithine SCHEMBL7105810 | 0.88 | GSR (0.69) | GSRNOD1FOLH1SLC6A5ARG1 | |
| Ornithine Aketoglutarate SCHEMBL7105807 | 0.88 | GSR (0.69) | GSRNOD1FOLH1SLC6A5ARG1 | |
| Norleucine SCHEMBL17423937 | 0.85 | GSR (0.61) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL3438650 | 0.84 | CPB2 (0.42) | NOD1FOLH1SLC6A5 | |
| SCHEMBL64149 | 0.83 | GSR (0.57) | GSROTCARG1ARG2 | |
| SCHEMBL432790 | 0.83 | GSR (0.57) | GSROTCARG1ARG2 | |
| SCHEMBL623369 | 0.83 | GSR (0.57) | GSROTCARG1ARG2 | |
| (S)-2-Aminoadipic Acid SCHEMBL15156054 | 0.82 | GSR (0.61) | GSRNOD1FOLH1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086092-A1 | BENZO(b)THIEPINE-1,1-DIOXIDE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THEIR USE | Aventis Pharma Deutschland GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064410-A1 | BENZO(b)THIEPINE-1,1-DIOXIDE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THEIR USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-12-16 | — | — | WO | disclosed |