Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.41 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13057114 | 0.86 | CPB2 (0.43) | CPB2FOLH1KISS1RNOD1ALB | |
| SCHEMBL19401625 | 0.86 | CPB2 (0.43) | CPB2FOLH1KISS1RNOD1ALB | |
| SCHEMBL434550 | 0.86 | CPB2 (0.43) | CPB2FOLH1KISS1RNOD1ALB | |
| SCHEMBL7922585 | 0.84 | GSR (0.57) | FOLH1NOD1SLC6A5 | |
| SCHEMBL17087044 | 0.82 | CPB2 (0.41) | CPB2FOLH1KISS1RNOD1ALB | |
| SCHEMBL16384290 | 0.82 | NOD1 (0.47) | FOLH1NOD1GNPATSLC6A5 | |
| SCHEMBL24410436 | 0.81 | CPB2 (0.40) | CPB2FOLH1KISS1RNOD1KDM4A | |
| SCHEMBL3438496 | 0.81 | FOLH1 (0.62) | FOLH1NOD1ALBSMN1; SMN2 | |
| SCHEMBL13595628 | 0.81 | FOLH1 (0.54) | CPB2FOLH1KISS1RNOD1ALB | |
| SCHEMBL21673279 | 0.81 | FOLH1 (0.54) | CPB2FOLH1KISS1RNOD1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2020-06-18 | — | — | US | disclosed |
| WO-2018195078-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-10-25 | — | — | WO | disclosed |
| EP-3263586-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | Northern Antibiotics Oy (FI) | 2018-01-03 | — | — | EP | disclosed |
| EP-3078672-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | Northern Antibiotics Oy (FI) | 2016-10-12 | — | — | EP | disclosed |
| EP-2057185-B1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2016-05-11 | — | — | EP | disclosed |
| US-9096649-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2015-08-04 | — | — | US | disclosed |
| US-9090669-B2 | Short fatty acid tail polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2015-07-28 | — | — | US | disclosed |
| US-9067974-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS OY (FI) | 2015-06-30 | — | — | US | disclosed |
| US-20140162937-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2014-06-12 | — | — | US | disclosed |
| US-20140142030-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2014-05-22 | — | — | US | disclosed |
| US-8680234-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS OY (FI) | 2014-03-25 | — | — | US | disclosed |
| US-8642535-B2 | Short fatty acid tail polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2014-02-04 | — | — | US | disclosed |
| US-8329645-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2012-12-11 | — | — | US | disclosed |
| US-20120283176-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2012-11-08 | — | — | US | disclosed |
| US-8193148-B2 | Short fatty acid tail polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2012-06-05 | — | — | US | disclosed |
| US-20100292136-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2010-11-18 | — | — | US | disclosed |
| US-7807637-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS OY (FI) | 2010-10-05 | — | — | US | disclosed |
| US-20090239792-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2009-09-24 | — | — | US | disclosed |
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2009-08-27 | — | — | US | disclosed |
| US-20080287345-A1 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS OY (FI) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239792-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | TLR5, TLR3, TLR2 | CPB2 1242/4885FOLH1 1149/4885KISS1R 4568/4885 |
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | C5, C9, C3AR1 | CPB2 345/4885FOLH1 1174/4885KISS1R 1211/4885 |
| US-20140162937-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | SLC11A2, TLR2, TLR5 | CPB2 152/4885FOLH1 710/4885KISS1R 2352/4885 |
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | DDOST, MGAM, MSN | CPB2 1548/4885FOLH1 2100/4885KISS1R 4622/4885 |
| US-20100292136-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | C5, C9, C3AR1 | CPB2 345/4885FOLH1 1174/4885KISS1R 1211/4885 |
| US-20140142030-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | VIP, ELOVL5, TLR5 | CPB2 2292/4885FOLH1 793/4885KISS1R 4459/4885 |
| US-20120283176-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | ELOVL5, TLR5, VIP | CPB2 2132/4885FOLH1 661/4885KISS1R 4507/4885 |
| US-20080287345-A1 | Polymyxin derivatives and uses thereof | C9, C5, C3AR1 | CPB2 322/4885FOLH1 1147/4885KISS1R 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.