SCHEMBL7922674

SCHEMBL7922674

NC(=O)NN1CCNC1=O

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 3/20 0.33
POLB P06746 1/20 0.33
KLK5 Q9Y337 1/20 0.33
FAAH O00519 1/20 0.33
NAAA Q02083 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 2/20 0.30
RAB9A P51151 1/20 0.30
GAA P10253 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11772103 0.88 KLK5 (0.40) POLBKLK5KDM4EGAA
SCHEMBL11533645 0.83
SCHEMBL9650548 0.83 ALDH1A1 (0.36) NPSR1ALDH1A1POLBFAAHNAAA
SCHEMBL11640116 0.81 ALDH1A1 (0.36) NPSR1ALDH1A1POLBFAAHNAAA
SCHEMBL15632425 0.81 NPSR1 (0.37) NPSR1ALDH1A1POLBFAAHNAAA
SCHEMBL11637411 0.81 NPSR1 (0.33) NPSR1ALDH1A1POLBFAAHNAAA
SCHEMBL11637407 0.77 ALDH1A1 (0.32) NPSR1ALDH1A1KMT2ARAB9A
SCHEMBL20125203 0.76 ALDH1A1 (0.34) NPSR1ALDH1A1POLBFAAHNAAA
SCHEMBL19426007 0.76 FAAH (0.39) NPSR1ALDH1A1FAAHNAAAKDM4E
SCHEMBL14866137 0.76 L3MBTL1 (0.36) NPSR1ALDH1A1POLBFAAHNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112469826-B Magnetic-based biopanning method by attachment of magnetic beads to cells (株)爱恩德生物 2024-02-09 CN disclosed
US-6224795-B1 CONDENSATION OF MELAMINE WITH FORMALDEHYDE FOR RESIN AND METHYL ETHERS IN WATER DISPERSION BASF AKTIENGESELLSCHAFT (DE) 2001-05-01 US disclosed
US-5942240-A SYNERGISTIC ANTIMICROBIAL MIXTURE COMPRISING A TERMINALLY CYANO-SUBSTITUTED DIHALOGENATED ALKANE AND A HETEROCYCLIC POLY-HYDROXYLATED LOWER ALKYLAMIDE; FOR COSMETIC AND PHARMACEUTICAL FORMULATIONS, HOUSEHOLD AND INDUSTRIAL CLEANER ISP CHEMICALS INC. (US) 1999-08-24 US disclosed
WO-1999038381-A1 ANTIMICROBIAL PRESERVATIVE COMPOSITION ISP CHEMICALS INC. (US) 1999-08-05 WO disclosed
US-5855878-A Cosmetic compositions containing hydrophobically modified nonionic polymer and unsaturated quaternary ammonium surfactant THE PROCTER & GAMBLE COMPANY (US) 1999-01-05 US disclosed
US-5843418-A Cosmetic compositions containing hydrophobically modified nonionic polymer and unsaturated quaternary ammonium surfactant THE PROCTER & GAMBLE CO. (US) 1998-12-01 US disclosed
CN-1040619-C Cosmetic compositions containing hydrophobically modified nonionic polymer and unsaturated quaternary ammonium surfactant PROCTER & GAMBLE (US) 1998-11-11 CN disclosed
US-5807543-A THICKENER BLEND THE PROCTER & GAMBLE CO. (US) 1998-09-15 US disclosed
US-5807545-A THICKENER BLEND THE PROCTER & GAMBLE CO. (US) 1998-09-15 US disclosed
EP-0576578-B1 COSMETIC COMPOSITIONS CONTAINING HYDROPHOBICALLY MODIFIED NONIONIC POLYMER AND UNSATURATED QUATERNARY AMMONIUM SURFACTANT PROCTER & GAMBLE (US) 1995-12-06 EP disclosed
WO-1993007848-A2 HAIR SETTING COMPOSITION WITH COMBINATION OF CATIONIC CONDITIONERS THE PROCTER & GAMBLE COMPANY (US) 1993-04-29 WO disclosed
CN-1067174-A The hair care and the cosmetic composition that contain specific surfactant PROCTER & GAMBLE (US) 1992-12-23 CN disclosed
WO-1992016187-A1 COSMETIC COMPOSITIONS CONTAINING HYDROPHOBICALLY MODIFIED NONIONIC POLYMER AND UNSATURATED QUATERNARY AMMONIUM SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1992-10-01 WO disclosed
US-5106609-A Hydrophobically modified nonionic water soluble polymer, water insoluble surfactant, compatible solvent THE PROCTER & GAMBLE COMPANY (US) 1992-04-21 US disclosed
US-5104646-A Hydrophobically modified nonionic water soluble polymer, water soluble surfactant, compatible solvent THE PROCTER & GAMBLE COMPANY (US) 1992-04-14 US disclosed
US-5100657-A Cellulose ether thickeners, surfactants, silicone and fatty alcohol conditioners THE PROCTER & GAMBLE COMPANY (US) 1992-03-31 US disclosed
WO-1991016878-A1 CLEAN CONDITIONING COMPOSITIONS FOR HAIR THE PROCTER & GAMBLE COMPANY (US) 1991-11-14 WO disclosed
EP-0412706-A2 Vehicle systems for use in cosmetic compostions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0412710-A2 Vehicle systems for use in cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
US-4032638-A Heterocyclic ureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-28 US disclosed