SCHEMBL7922689

SCHEMBL7922689

O=P.c1ccc(-c2cccc3c2-c2ccccc2-3)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
BACE1 P56817 1/20 0.42
LMNA P02545 3/20 0.42
MAPT P10636 3/20 0.42
HTT P42858 2/20 0.42
MEN1 O00255 1/20 0.42
APAF1 O14727 1/20 0.42
NPC1 O15118 1/20 0.42
THRB P10828 1/20 0.42
XBP1 P17861 1/20 0.42
PTBP1 P26599 1/20 0.42
RAB9A P51151 1/20 0.42
GALK1 P51570 1/20 0.42
BLM P54132 1/20 0.42
SMAD3 P84022 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2167186 0.93 ALDH1A1 (0.46) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL2373718 0.93 ALDH1A1 (0.46) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL30395776 0.93 ALDH1A1 (0.46) HNF4AHDAC4HDAC2HDAC8HDAC6
Hydrogen Sulfide SCHEMBL27549591 0.90 ALDH1A1 (0.44) HNF4AHDAC4HDAC2HDAC8HDAC6
Phosphine SCHEMBL27403569 0.90 ALDH1A1 (0.44) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL29108665 0.88 ALDH1A1 (0.45) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL30355086 0.87 ALDH1A1 (0.46) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL11762758 0.87 ALDH1A1 (0.46) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL2422115 0.85 ALDH1A1 (0.48) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL6800360 0.84 ALDH1A1 (0.44) HNF4AHDAC4HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1157360-C Preparation of diaryl carbonate ��˲���ʽ���� 2004-07-14 CN disclosed
CN-1140494-C Preparation of diaryl carbonate 宇部兴产株式会社 2004-03-03 CN disclosed
CN-1128782-C Catalyst for decarbonylation reaction UBE INDUSTRIES (JP) 2003-11-26 CN disclosed
EP-0834496-B1 Preparation of diaryl carbonate UBE INDUSTRIES (JP) 2001-08-16 EP disclosed
EP-0834495-B1 Process for preparing diaryl carbonate UBE INDUSTRIES (JP) 2000-12-27 EP disclosed
US-5892091-A PHOSPHOROUS CATALYSTS AND HALOGEN ATOMS UBE INDUSTRIES, LTD. (JP) 1999-04-06 US disclosed
US-5892089-A FROM DIARYL OXALATE IN LIQUID PHASE BY DECARBONYLATION USING ORGANIC PHOSHORUS COMPOUND CATALYST UBE INDUSTRIES, LTD. (JP) 1999-04-06 US disclosed
EP-0737665-B1 Process for preparation of diaryl carbonate UBE INDUSTRIES (JP) 1998-10-21 EP disclosed
US-5792883-A Preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-08-11 US disclosed
CN-1181373-A Preparation of diaryl carbonate UBE INDUSTRIES (JP) 1998-05-13 CN disclosed
CN-1181374-A Preparation of diaryl carbonate UBE INDUSTRIES (JP) 1998-05-13 CN disclosed
CN-1179414-A Catalyst for decarbonylation reaction UBE INDUSTRIES (JP) 1998-04-22 CN disclosed
EP-0834496-A1 Preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed
EP-0834495-A1 Process for preparing diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed
EP-0826658-A1 Catalyst for decarbonylation reaction UBE INDUSTRIES, LTD. (JP) 1998-03-04 EP disclosed
US-5648510-A DECARBONYLATION OF OXALATE UBE INDUSTRIES, LTD. (JP) 1997-07-15 US disclosed
EP-0737665-A1 Process for preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1996-10-16 EP disclosed