Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 3/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257927 | 0.82 | ABCC8 (0.49) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL7931902 | 0.82 | KDM4E (0.52) | ABCC8KCNJ11ALDH1A1CA12CA2 | |
| SCHEMBL7929286 | 0.80 | ABCC8 (0.45) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL7931865 | 0.76 | ABCC8 (0.41) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL7932571 | 0.71 | ABCC8 (0.40) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL7692864 | 0.67 | NOX1 (0.39) | ALDH1A1MAPTKMT2A | |
| SCHEMBL11467613 | 0.65 | CA12 (0.42) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL4256305 | 0.65 | CA12 (0.44) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL4266841 | 0.63 | KDM4E (0.56) | ABCC8KCNJ11ALDH1A1CA12CA2 | |
| SCHEMBL20664932 | 0.61 | KMT2A (0.46) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | claimed |
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | disclosed |