Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | USP8 | P40818 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266841 | 0.83 | KDM4E (0.56) | KDM4EPOLBMAPTKMT2ACA12 | |
| SCHEMBL7922807 | 0.82 | ABCC8 (0.43) | KDM4EPOLBMAPTKMT2ACA12 | |
| SCHEMBL7929271 | 0.81 | KDM4E (0.53) | KDM4EPOLBMAPTKMT2ACA12 | |
| SCHEMBL7930935 | 0.78 | KDM4E (0.53) | KDM4EPOLBMAPTKMT2ACA12 | |
| SCHEMBL7685864 | 0.68 | SNCA (0.59) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL8878883 | 0.64 | MAPT (0.72) | KDM4EPOLBMAPTKMT2ACA12 | |
| SCHEMBL9813147 | 0.64 | MAPT (0.63) | KDM4EPOLBMAPTKMT2ACA12 | |
| SCHEMBL9829945 | 0.64 | KDM4E (0.56) | KDM4EPOLBMAPTKMT2ACA12 | |
| SCHEMBL9813220 | 0.63 | KMT2A (0.58) | KDM4EPOLBMAPTKMT2ACA12 | |
| SCHEMBL29766352 | 0.63 | CA12 (1.00) | KDM4EPOLBMAPTKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | claimed |
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | disclosed |