Styrene

Styrene

SCHEMBL7923087

C=C(C)C(=O)OC.C=CC#N.C=Cc1ccccc1.O=C1C=CC(=O)N1c1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 5/20 0.36
ALDH1A1 P00352 3/20 0.35
HSP90AA1 P07900 1/20 0.32
FAAH O00519 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
DDAH1 O94760 1/20 0.30
ATM Q13315 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28850634 0.95 MGLL (0.40) MGLLALDH1A1HSP90AA1FAAHKMT2A
Styrene SCHEMBL3838357 0.94 MGLL (0.41) MGLLALDH1A1HSP90AA1FAAHKMT2A
Styrene SCHEMBL2778795 0.92 ALDH1A1 (0.36) ALDH1A1KMT2AMEN1MAPT
Styrene SCHEMBL27514094 0.89 MGLL (0.37) MGLLALDH1A1HSP90AA1FAAHKMT2A
Styrene SCHEMBL20970201 0.88 MGLL (0.46) MGLLALDH1A1HSP90AA1FAAHKMT2A
Acrylonitrile SCHEMBL27930297 0.88 MGLL (0.46) MGLLALDH1A1HSP90AA1FAAHKMT2A
Styrene SCHEMBL2774651 0.85 ALDH1A1 (0.42) ALDH1A1KMT2AMEN1MAPT
Styrene SCHEMBL8712542 0.85 MGLL (0.38) MGLLALDH1A1HSP90AA1FAAHKMT2A
Styrene SCHEMBL28228550 0.83 MGLL (0.41) MGLLALDH1A1HSP90AA1FAAHKMT2A
Styrene SCHEMBL9482333 0.83 ALDH1A1 (0.40) ALDH1A1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1221612-C Polycarbonate resin blends containing titanium dioxide GEN ELECTRIC (US) 2005-10-05 CN disclosed
CN-1331728-A Polycarbonate resin blends contg. titanium dioxide GEN ELECTRIC (US) 2002-01-16 CN disclosed
EP-1123350-A1 POLYCARBONATE RESIN BLENDS CONTAINING TITANIUM DIOXIDE GENERAL ELECTRIC COMPANY (US) 2001-08-16 EP disclosed
US-6133360-A INJECTION MOLDING USING A TITANIUM DIOXIDE CONTAINING POLYCARBONATE RESIN WHREIN TITANIUM DIOXIDE IS COATED WITH A SINGLE COAT AND FORMING MOLDINGS HAVING NO STREAKING GENERAL ELECTRIC COMPANY (US) 2000-10-17 US disclosed
WO-2000024828-A1 POLYCARBONATE RESIN BLENDS CONTAINING TITANIUM DIOXIDE GENERAL ELECTRIC COMPANY (US) 2000-05-04 WO disclosed
EP-0629498-B1 Multi layered product comprising an ABS layer with a low rubber content and an ABS layer with a high rubber content GEN ELECTRIC (US) 1998-10-07 EP disclosed
US-5492966-A BI-LOBED: ONE RIGID, ONE RUBBERY; RUBBER LOBES EXHIBIT AFFINITY FOR EACH OTHER AND TEND TO AGGLOMERATE DURING COMPOUNDING TO GIVE LARGE RUBBER PARTICLE SIZES WITH REDUCED GLOSS GENERAL ELECTRIC COMPANY (US) 1996-02-20 US disclosed
US-5486407-A High rubber backing multi-layer ABS system which exhibits improved chemical resistance to HCFC blowing agents GENERAL ELECTRIC CO. (US) 1996-01-23 US disclosed
EP-0629498-A1 Multi layered product comprising an ABS layer with a low rubber content and an ABS layer with a high rubber content GENERAL ELECTRIC COMPANY (US) 1994-12-21 EP disclosed
EP-0564240-A1 Impact modified resin compositions GENERAL ELECTRIC COMPANY (US) 1993-10-06 EP disclosed
US-5047470-A Thermoplastic Blends GENERAL ELECTRIC COMPANY (US) 1991-09-10 US disclosed
EP-0363814-A2 Low-temperature impact blends of polycarbonate, graft copolymer and rigid copolymer GENERAL ELECTRIC COMPANY (US) 1990-04-18 EP disclosed