Styrene

Styrene

SCHEMBL8712542

C=CC#N.C=Cc1ccccc1.CC=C(C)C(=O)O.O=C1C=CC(=O)N1c1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.38
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
AKR1C3 P42330 1/20 0.33
FAAH O00519 2/20 0.33
DDAH1 O94760 1/20 0.32
HSP90AA1 P07900 2/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
ATM Q13315 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1830884 0.91 AKR1C3 (0.40) MEN1KMT2AAKR1C3ALDH1A1HTT
Styrene SCHEMBL7923087 0.85 MGLL (0.36) MGLLMEN1KMT2AFAAHDDAH1
Styrene SCHEMBL7177772 0.84 AKR1C3 (0.46) MEN1KMT2AAKR1C3ALDH1A1HTT
Styrene SCHEMBL531225 0.84 AKR1C3 (0.46) MEN1KMT2AAKR1C3ALDH1A1HTT
Styrene SCHEMBL150226 0.82 MGLL (0.56) MGLLFAAHDDAH1HSP90AA1ALDH1A1
Styrene SCHEMBL27996115 0.82 MGLL (0.56) MGLLFAAHDDAH1HSP90AA1ALDH1A1
Maleic Anhydride SCHEMBL9076211 0.82 MGLL (0.56) MGLLFAAHDDAH1HSP90AA1ALDH1A1
Styrene SCHEMBL1070534 0.81 MGLL (0.58) MGLLFAAHDDAH1HSP90AA1ALDH1A1
Styrene SCHEMBL301613 0.81 AKR1C3 (0.49) MEN1KMT2AAKR1C3ALDH1A1HTT
Styrene SCHEMBL20338077 0.79 MGLL (0.55) MGLLFAAHDDAH1HSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0629498-B1 Multi layered product comprising an ABS layer with a low rubber content and an ABS layer with a high rubber content GEN ELECTRIC (US) 1998-10-07 EP disclosed
EP-0629498-A1 Multi layered product comprising an ABS layer with a low rubber content and an ABS layer with a high rubber content GENERAL ELECTRIC COMPANY (US) 1994-12-21 EP disclosed