Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929844 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HPGDHTTTAS1R3TAS1R1 | |
| SCHEMBL15384066 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDHTTMAPTUSP2 | |
| SCHEMBL23095240 | 0.76 | HTT (0.53) | ALDH1A1HPGDHTTMAPTUSP2 | |
| SCHEMBL30669506 | 0.75 | KMT2A (0.48) | ALDH1A1HPGDHTTMAPTTP53 | |
| SCHEMBL19194019 | 0.75 | EDNRA (0.48) | ALDH1A1HPGDHTTEDNRAMAPT | |
| SCHEMBL1921332 | 0.73 | NPC1 (0.62) | TAS1R3TAS1R1MAPK1MEN1KMT2A | |
| SCHEMBL1921333 | 0.73 | NPC1 (0.62) | TAS1R3TAS1R1MAPK1MEN1KMT2A | |
| SCHEMBL13606614 | 0.73 | NPC1 (0.62) | TAS1R3TAS1R1MAPK1MEN1KMT2A | |
| SCHEMBL3846689 | 0.71 | SMN1; SMN2 (0.58) | HTTMAPTMAPK1TP53MEN1 | |
| SCHEMBL13606613 | 0.71 | SMN1; SMN2 (0.58) | HTTMAPTMAPK1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268831-B2 | Compounds derived from 2-(3-methylenedioxy)-benzoyl indol | BIOLAB SANUS FARMACEUTICA LTDA. (BR) | 2012-09-18 | — | — | US | disclosed |
| US-20110195976-A1 | COMPOUNDS DERIVED FROM 2-(3-METHYLENEDIOXY)-BENZOYL INDOL | BIOLAB SANUS FARMACEUTICA LTDA. (BR) | 2011-08-11 | — | — | US | disclosed |
| WO-2010037190-A1 | COMPOUNDS DERIVED FROM 2-(3-METHYLENEDIOXY)-BENZOYL INDOL | BIOLAB SANUS FARMACÊUTICA LTDA. (BR) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195976-A1 | COMPOUNDS DERIVED FROM 2-(3-METHYLENEDIOXY)-BENZOYL INDOL | HTR5A, IDO1, IDO2 | ALDH1A1 708/4885HPGD 316/4885HTT 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.