Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15384066 | 0.81 | ALDH1A1 (0.57) | HTTALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL2298131 | 0.76 | ALDH1A1 (0.43) | HTTALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL2300620 | 0.76 | ALDH1A1 (0.43) | HTTALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL7929844 | 0.76 | ALDH1A1 (0.49) | HTTALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL7923355 | 0.76 | ALDH1A1 (0.49) | HTTALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL2298105 | 0.76 | ALDH1A1 (0.43) | HTTALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL21419459 | 0.74 | ALDH1A1 (0.56) | HTTALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL7477207 | 0.73 | PTGS2 (0.53) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2002751 | 0.71 | FOLH1 (0.71) | HTTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5279031 | 0.71 | MAP2 (0.57) | ALDH1A1HPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947572-B2 | Engineered imine reductases and methods for the reductive amination of ketone and amine compounds | CODEXIS, INC. (US) | 2021-03-16 | — | — | US | disclosed |