Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821903 | 0.88 | KMT2A (0.48) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL7936379 | 0.88 | KMT2A (0.48) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL6395621 | 0.74 | MEN1 (0.66) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL10031595 | 0.74 | KMT2A (0.66) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL9975770 | 0.74 | KMT2A (0.66) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL7924339 | 0.70 | KMT2A (0.50) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL17532466 | 0.70 | ALDH1A1 (0.50) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL7930188 | 0.70 | ELANE (0.42) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL12119582 | 0.69 | ALDH1A1 (0.77) | KMT2AMEN1ALDH1A1TSHRUSP2 | |
| SCHEMBL17532457 | 0.69 | ALDH1A1 (0.77) | KMT2AMEN1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800551-B1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL NV (NL) | 2001-06-13 | — | — | EP | claimed |
| US-5844049-A | Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds | AKZO NOBEL NV (NL) | 1998-12-01 | — | — | US | claimed |
| EP-0800551-A1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | Akzo Nobel N.V. (NL) | 1997-10-15 | — | — | EP | claimed |
| WO-1996020246-A1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL N.V. (NL) | 1996-07-04 | — | — | WO | claimed |