Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923401 | 0.88 | KMT2A (0.42) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL10031595 | 0.86 | KMT2A (0.66) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL9975770 | 0.86 | KMT2A (0.66) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL7936379 | 0.80 | KMT2A (0.48) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL17532466 | 0.77 | ALDH1A1 (0.50) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL7924339 | 0.77 | KMT2A (0.50) | KMT2AMEN1CMA1ALDH1A1TSHR | |
| SCHEMBL14086649 | 0.76 | KMT2A (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12119582 | 0.76 | ALDH1A1 (0.77) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL17532457 | 0.76 | ALDH1A1 (0.77) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12119605 | 0.73 | ALDH1A1 (0.79) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252862-B2 | Silane coupling agents for filled rubbers | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8252862-B2 | Silane coupling agents for filled rubbers | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| EP-2190912-B1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
| US-20100261826-A1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2010-10-14 | — | — | US | disclosed |
| US-20100261826-A1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2010-10-14 | — | — | US | disclosed |
| US-7723409-B2 | Coupling agents between filler and elastomer | CIBA SPECIALTY CHEM. CORP. (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723409-B2 | Coupling agents between filler and elastomer | CIBA SPECIALTY CHEM. CORP. (US) | 2010-05-25 | — | — | US | disclosed |
| WO-2010006889-A2 | COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2010-01-21 | — | — | WO | disclosed |
| EP-1727858-B1 | COUPLING AGENTS BETWEEN FILLER AND ELASTOMER | BASF SE (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2009034016-A1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (CH) | 2009-03-19 | — | — | WO | disclosed |
| US-20080287578-A1 | Coupling Agents Between Filler and Elastomer | CIBA SPECIALTY CHEMICALS CORP. | 2008-11-20 | — | — | US | disclosed |
| US-20080287578-A1 | Coupling Agents Between Filler and Elastomer | CIBA SPECIALTY CHEMICALS CORP. | 2008-11-20 | — | — | US | disclosed |
| WO-2007039416-A1 | FILLED RUBBER COMPOUNDS WITH IMPROVED PROCESSABILITY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | RER1, RIF1, REV1 | KMT2A 2949/4885MEN1 1869/4885CMA1 355/4885 |
| US-20100261826-A1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | RER1, REV1, RIOX2 | KMT2A 1874/4885MEN1 3889/4885CMA1 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.