Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16087725 | 0.89 | ACHE (0.52) | ACHEALOX5L3MBTL1MAPTHPGD | |
| SCHEMBL12431884 | 0.89 | ACHE (0.56) | ACHEL3MBTL1MAPTHPGDMAPK1 | |
| SCHEMBL15151735 | 0.84 | MAPT (0.43) | ACHEL3MBTL1MAPTHPGDMAPK1 | |
| SCHEMBL195058 | 0.84 | PTGS2 (0.46) | ACHEPTGS2TUBB1TUBB4ATUBB | |
| SCHEMBL12433117 | 0.83 | ACHE (0.54) | ACHEALOX5L3MBTL1MAPTHPGD | |
| SCHEMBL12432397 | 0.81 | ACHE (0.52) | ACHEALOX5SYK | |
| SCHEMBL171116 | 0.79 | ACHE (1.00) | ACHEPTGS2TUBB1TUBB4ATUBB | |
| SCHEMBL10053938 | 0.79 | ACHE (0.58) | ACHEPTGS2TUBB1TUBB4ATUBB | |
| SCHEMBL11890493 | 0.78 | L3MBTL4 (0.66) | ACHEL3MBTL1MAPTHPGDMAPK1 | |
| SCHEMBL11963361 | 0.78 | ACHE (0.61) | ACHEL3MBTL1MAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981803-A | TREATING TRICHLOROMETHYLARENE WITH WATER IN THE PRESENCE OF A LEWIS ACID AT TEMPERATURES BELOW 80 DEGREES C TO OBTAIN A REACTION MIXTURE COMPRISING A CHLORO-BENZOYLCHLORIDE, ADDING A SUBSTITUTED BENZENE DERIVATIVE, ACYLATING | AMERICAN CYANAMID COMPANY (US) | 1999-11-09 | — | — | US | claimed |
| EP-0854128-B1 | Process for the preparation of chloro-benzoyl chlorides | BASF AG (DE) | 2001-07-25 | — | — | EP | disclosed |
| US-6069274-A | REACTING A CHLORO-TRICHLOROMETHYLBENZENE WITH WATER IN THE PRESENCE OF FERRIC TRICHLORIDE | AMERICAN CYANAMID COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| US-5981803-A | TREATING TRICHLOROMETHYLARENE WITH WATER IN THE PRESENCE OF A LEWIS ACID AT TEMPERATURES BELOW 80 DEGREES C TO OBTAIN A REACTION MIXTURE COMPRISING A CHLORO-BENZOYLCHLORIDE, ADDING A SUBSTITUTED BENZENE DERIVATIVE, ACYLATING | AMERICAN CYANAMID COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0854128-A1 | Process for the preparation of chloro-benzoyl chlorides | American Cyanamid Company (US) | 1998-07-22 | — | — | EP | disclosed |