SCHEMBL6798554

SCHEMBL6798554

COC(OC)(OC(c1ccccc1)(c1ccccc1)c1ccccc1)C1CC(O)CN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.37
FABP7 O15540 2/20 0.35
MDM4 O15151 2/20 0.35
TP53 P04637 2/20 0.35
KMT2A Q03164 2/20 0.34
RIPK1 Q13546 1/20 0.33
MDM2 Q00987 2/20 0.33
OPRD1 P41143 1/20 0.33
F10 P00742 1/20 0.33
POLB P06746 1/20 0.33
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6796420 1.00 FABP5 (0.37) FABP5FABP7MDM4TP53KMT2A
SCHEMBL8663156 0.86 KMT2A (0.44) MDM4TP53KMT2AMDM2OPRD1
SCHEMBL8729183 0.84 LMNA (0.39) FABP5FABP7MDM4TP53KMT2A
SCHEMBL6853795 0.84 LMNA (0.39) FABP5FABP7MDM4TP53KMT2A
SCHEMBL8729229 0.84 LMNA (0.39) FABP5FABP7MDM4TP53KMT2A
SCHEMBL8660413 0.84 POLB (0.46) POLB
SCHEMBL6802273 0.83 MDM4 (0.34) FABP5FABP7MDM4TP53OPRD1
SCHEMBL6856330 0.82 FABP5 (0.33) FABP5FABP7MDM4TP53
SCHEMBL8660376 0.79 RIPK1 (0.37) KMT2ARIPK1
SCHEMBL6858060 0.79 FABP5 (0.37) FABP5FABP7MDM4TP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11920040-B2 Carborhodamine compounds and methods of preparation thereof ELITECHGROUP MDX LLC (US) 2024-03-05 US disclosed
US-20230105320-A1 CARBORHODAMINE COMPOUNDS AND METHODS OF PREPARATION THEREOF ELITECHGROUP MDX LLC (US) 2023-04-06 US disclosed
US-11618826-B2 Carborhodamine compounds and methods of preparation thereof ELITECHGROUP MDX LLC (US) 2023-04-04 US disclosed
US-20220119424-A1 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITechGroup MDX, LLC (US) 2022-04-21 US disclosed
US-11242554-B2 Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes ELITECHGROUP, INC. (US) 2022-02-08 US disclosed
US-20220002549-A1 CARBORHODAMINE COMPOUNDS AND METHODS OF PREPARATION THEREOF ELITECHGROUP, INC. (US) 2022-01-06 US disclosed
US-11155713-B2 Carborhodamine compounds and methods of preparation thereof ELITECHGROUP, INC. (US) 2021-10-26 US disclosed
EP-3802526-A1 CARBORHODAMINE COMPOUNDS AND METHODS OF PREPARATION THEREOF ELITechGroup, Inc. (US) 2021-04-14 EP disclosed
US-20200299755-A1 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2020-09-24 US disclosed
US-10738346-B2 Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes ELITECHGROUP, INC. (US) 2020-08-11 US disclosed
US-6316626-B1 Amine compounds and combinatorial libraries comprising same ISIS PHARMACEUTICALS, INC. 2001-11-13 US disclosed
US-6184389-B1 FEATURE A PLURALITY OF FUNCTIONAL GROUPS ATTACHED TO BACKBONE AND PHOSPHORAMIDATE SITES ISIS PHARMACEUTICALS, INC. 2001-02-06 US disclosed
WO-1999012034-A1 AMINE COMPOUNDS AND COMBINATORIAL LIBRARIES COMPRISING SAME ISIS PHARMACEUTICALS, INC. (US) 1999-03-11 WO disclosed
EP-0865439-A4 COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS ISIS PHARMACEUTICALS INC (US) 1998-11-11 EP disclosed
EP-0865439-A1 COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS ISIS PHARMACEUTICALS, INC. (US) 1998-09-23 EP disclosed
US-5714606-A OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS ISIS PHARMACEUTICALS, INC. (US) 1998-02-03 US disclosed
EP-0739335-A4 PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS ISIS PHARMACEUTICALS INC (US) 1997-04-02 EP disclosed
WO-1996040672-A1 COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS ISIS PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
EP-0739335-A1 PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS ISIS PHARMACEUTICALS, INC. (US) 1996-10-30 EP disclosed
WO-1995018792-A1 PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS ISIS PHARMACEUTICALS, INC. (US) 1995-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220119424-A1 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES DNTT, NME2, DUT FABP5 759/4885FABP7 757/4885MDM4 525/4885
US-20200299755-A1 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES DNTT, NME2, DUT FABP5 759/4885FABP7 757/4885MDM4 525/4885
US-10738346-B2 Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes DNTT, NME2, DUT FABP5 759/4885FABP7 757/4885MDM4 525/4885
US-11242554-B2 Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes DNTT, NME2, DUT FABP5 759/4885FABP7 757/4885MDM4 525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.