Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17122910 | 0.92 | LTA4H (0.48) | LTA4HNR5A1PARP10ESR1L3MBTL1 | |
| SCHEMBL1271045 | 0.84 | ESR1 (0.59) | LTA4HNR5A1ESR1L3MBTL1 | |
| SCHEMBL6851369 | 0.82 | KMT2A (0.58) | — | |
| SCHEMBL30530685 | 0.82 | KDM4E (0.53) | LTA4HPARP10 | |
| SCHEMBL6850906 | 0.82 | L3MBTL1 (0.65) | DRD2DRD4DRD3PARP10L3MBTL1 | |
| SCHEMBL7917839 | 0.82 | MAPT (0.61) | PARP10L3MBTL1 | |
| SCHEMBL1326062 | 0.82 | PARP10 (0.61) | LTA4HPARP10L3MBTL1 | |
| SCHEMBL9453956 | 0.81 | NR5A1 (0.51) | LTA4HNR5A1ESR1 | |
| Hydrochloric Acid SCHEMBL6851370 | 0.81 | KMT2A (0.56) | — | |
| SCHEMBL8449777 | 0.81 | LTA4H (0.50) | LTA4HPARP10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039256-A1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |