Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | PROC | P04070 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930390 | 0.91 | TACR1 (0.36) | NAAATNKSTNKS2TACR1PLG | |
| SCHEMBL7932739 | 0.75 | RIPK1 (0.38) | NAAACTSSCTSKCTSBCTSL | |
| SCHEMBL7932706 | 0.75 | CASR (0.30) | — | |
| SCHEMBL7923927 | 0.71 | GHSR (0.31) | GHSR | |
| SCHEMBL7791777 | 0.70 | GHSR (0.61) | GHSR | |
| SCHEMBL7930376 | 0.70 | GHSR (0.32) | GHSR | |
| SCHEMBL7930347 | 0.69 | GHSR (0.37) | GHSR | |
| SCHEMBL7932143 | 0.69 | GHSR (0.38) | GHSR | |
| SCHEMBL7936524 | 0.69 | GHSR (0.39) | GHSR | |
| SCHEMBL8332959 | 0.68 | RIPK1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211174-B1 | OSTEOPOROSIS; MILK PRODUCTION AND CARCASS QUALITY IN LIVESTOCK; SHORT STATURE; METABOLIC DISORDERS | MERCK & CO., INC. | 2001-04-03 | — | — | US | disclosed |