Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930391 | 0.88 | RIPK1 (0.37) | RIPK1CTSKIDO1TDO2CA1 | |
| SCHEMBL8332959 | 0.84 | RIPK1 (0.49) | RIPK1IDO1TDO2CA1CA2 | |
| SCHEMBL7795967 | 0.81 | RIPK1 (0.42) | RIPK1IDO1TDO2CA1CA2 | |
| SCHEMBL8331733 | 0.81 | RIPK1 (0.42) | RIPK1IDO1TDO2CA1CA2 | |
| SCHEMBL7794597 | 0.78 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL8713363 | 0.76 | CCKBR (0.36) | RIPK1IDO1 | |
| SCHEMBL7923932 | 0.75 | NAAA (0.35) | CTSKPARP1NAAAITGB3ITGA2B | |
| SCHEMBL7930390 | 0.72 | TACR1 (0.36) | NAAA | |
| SCHEMBL9025094 | 0.71 | RIPK1 (0.48) | RIPK1IDO1TDO2CA1CA2 | |
| SCHEMBL9025122 | 0.71 | RIPK1 (0.48) | RIPK1IDO1TDO2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211174-B1 | OSTEOPOROSIS; MILK PRODUCTION AND CARCASS QUALITY IN LIVESTOCK; SHORT STATURE; METABOLIC DISORDERS | MERCK & CO., INC. | 2001-04-03 | — | — | US | disclosed |