SCHEMBL7924337

SCHEMBL7924337

CO[Si](CCCc1cccc(C)c1SSc1c(C)cccc1CCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
PTGS2 P35354 1/20 0.33
SCN8A Q9UQD0 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
CHRM2 P08172 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8826411 0.94 ALOX5 (0.31) ALOX5PTGS2
SCHEMBL8826397 0.94 ALOX5 (0.31) ALOX5PTGS2
SCHEMBL8826216 0.93 ALOX5 (0.31) ALOX5PTGS2
SCHEMBL8826563 0.93 ALOX5 (0.31) ALOX5PTGS2
SCHEMBL8826625 0.93 ALOX5 (0.31) ALOX5PTGS2
SCHEMBL8826753 0.93 ALOX5 (0.31) ALOX5PTGS2
SCHEMBL7919332 0.85 SCN4A (0.30)
SCHEMBL1639192 0.80 PTGS2 (0.38) ALOX5PTGS2TAAR1
SCHEMBL8826644 0.80
SCHEMBL8826450 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218561-B1 REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. THE GOODYEAR TIRE & RUBBER COMPANY 2001-04-17 US claimed
US-5675014-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-07 US claimed
US-5663358-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 US claimed
EP-0785206-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP claimed
EP-0785207-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP claimed
EP-0718302-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-06-26 EP claimed
US-5440064-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-08-08 US claimed
US-6218561-B1 REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. THE GOODYEAR TIRE & RUBBER COMPANY 2001-04-17 US disclosed
US-5684171-A FROM DITHIODIMORPHOLINE AND A MERCAPTOSILANE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-11-04 US disclosed
US-5684172-A REACTING BENZOTHIAZOLYL MORPHOLINYL DISULFIDE WITH A MERCAPTOALKYLALKOXYSILANE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-11-04 US disclosed
US-5675014-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-07 US disclosed
US-5663358-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 US disclosed
EP-0785207-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP disclosed
EP-0785206-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP disclosed
EP-0718302-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-06-26 EP disclosed
US-5440064-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-08-08 US disclosed