SCHEMBL1639192

SCHEMBL1639192

CO[Si](CCCc1cccc(CCC[Si](OC)(OC)OC)c1CCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.38
ALOX5 P09917 1/20 0.38
MTNR1A P48039 7/20 0.33
MTNR1B P49286 7/20 0.33
PPARA Q07869 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4426628 0.88 ALOX5 (0.33) PTGS2ALOX5MTNR1AMTNR1BPPARA
SCHEMBL1639308 0.86 MTNR1A (0.40) PTGS2ALOX5MTNR1AMTNR1BTAAR1
SCHEMBL1639326 0.83 PTGS2 (0.33) PTGS2ALOX5MTNR1AMTNR1BPPARA
SCHEMBL30217865 0.80 GLS (0.31)
SCHEMBL7924337 0.80 ALOX5 (0.33) PTGS2ALOX5TAAR1
SCHEMBL8736802 0.79 CYP3A4 (0.37) TAAR1
SCHEMBL1406060 0.79 AKR1B1 (0.47) MTNR1A
SCHEMBL11835696 0.78 MTNR1A (0.35) PTGS2ALOX5MTNR1AMTNR1BTAAR1
SCHEMBL16198395 0.78 ALDH1A1 (0.39) PTGS2ALOX5TAAR1
SCHEMBL4465343 0.78 MPO (0.48) PTGS2ALOX5TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed