Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049682 | 0.81 | KIF11 (0.43) | KIF11KCNH2CA4KMT2ALTA4H | |
| SCHEMBL21562153 | 0.80 | CA4 (0.46) | KIF11KCNH2CA4KMT2ALTA4H | |
| SCHEMBL17173364 | 0.80 | CA4 (0.46) | KIF11KCNH2CA4KMT2ALTA4H | |
| SCHEMBL8934873 | 0.79 | NR3C2 (0.36) | KIF11CA4KMT2ACYP2D6ADRA2A | |
| SCHEMBL20371105 | 0.78 | KIF11 (0.53) | KIF11KCNH2KMT2ASLC6A4 | |
| SCHEMBL28346610 | 0.78 | KIF11 (0.44) | KIF11KCNH2CA4KMT2ALTA4H | |
| SCHEMBL4436554 | 0.77 | KIF11 (0.42) | KIF11KCNH2CA4KMT2ALTA4H | |
| SCHEMBL4421575 | 0.76 | KIF11 (0.45) | KIF11KCNH2KMT2ALTA4HMEN1 | |
| SCHEMBL13388489 | 0.76 | KIF11 (0.50) | KIF11KCNH2 | |
| SCHEMBL7010039 | 0.75 | KMT2A (0.44) | KIF11KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819134-B1 | COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES, METHOD FOR PREPARING SAME, AND SYNTHON USED THEREIN | GENSET SA (FR) | 2001-07-18 | — | — | EP | disclosed |
| US-6187913-B1 | Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method | GENSET (FR) | 2001-02-13 | — | — | US | disclosed |
| EP-0819134-A1 | COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES, METHOD FOR PREPARING SAME, AND SYNTHON USED THEREIN | GENSET SA (FR) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031523-A1 | COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES, METHOD FOR PREPARING SAME, AND SYNTHON USED THEREIN | GENSET (FR) | 1996-10-10 | — | — | WO | disclosed |