SCHEMBL7010039

SCHEMBL7010039

COc1ccc(C(OC(C)S(=O)(=O)C(C)O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.44
KIF11 P52732 9/20 0.41
HSD11B1 P28845 1/20 0.39
MMP1 P03956 2/20 0.38
MMP2 P08253 2/20 0.38
MMP3 P08254 2/20 0.38
KCNH2 Q12809 1/20 0.38
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
HTT P42858 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ACP3 P15309 1/20 0.37
EGFR P00533 1/20 0.36
ERBB2 P04626 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655114 0.87 KMT2A (0.42) KMT2AKIF11HSD11B1KCNH2HTT
SCHEMBL7008086 0.80 KMT2A (0.43) KMT2AKIF11HSD11B1MMP1MMP2
SCHEMBL7049682 0.78 KIF11 (0.43) KMT2AKIF11KCNH2HTTCES2
SCHEMBL21562153 0.77 CA4 (0.46) KMT2AKIF11KCNH2
SCHEMBL17173364 0.77 CA4 (0.46) KMT2AKIF11KCNH2
SCHEMBL7924524 0.75 KIF11 (0.47) KMT2AKIF11KCNH2
SCHEMBL9306492 0.75 SLC6A11 (0.45) KMT2AKIF11HSD11B1
SCHEMBL28346610 0.74 KIF11 (0.44) KMT2AKIF11KCNH2
SCHEMBL4436554 0.73 KIF11 (0.42) KMT2AKIF11KCNH2
SCHEMBL28783455 0.73 KMT2A (0.47) KMT2AKIF11HSD11B1KCNH2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254149-A1 Chemical Phosphorylation Reagents, Preparation, and Their Uses OLIX US, INC. 2024-08-01 US disclosed
EP-4341270-A1 CHEMICAL PHOSPHORYLATION REAGENTS, PREPARATION, AND THEIR USES Olix US, Inc. (US) 2024-03-27 EP disclosed
CN-117580848-A Chemical phosphorylating reagent, preparation and use thereof 奥利克斯美国公司 2024-02-20 CN disclosed
WO-2022246196-A1 CHEMICAL PHOSPHORYLATION REAGENTS, PREPARATION, AND THEIR USES OLIX US, INC. (US) 2022-11-24 WO disclosed
EP-0816368-B1 Chemical phoshorylation of oligonucleotides and reactants used therefor GLEN RES CORP (US) 2003-01-08 EP disclosed
US-5959090-A FORMING PHOSPHORAMIDITE COMPOUNDS FROM PHOSPHORYLATION GLEN RESEARCH CORPORATION (US) 1999-09-28 US disclosed
EP-0816368-A1 Chemical phoshorylation of oligonucleotides and reactants used therefor Glen Research Corporation (US) 1998-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254149-A1 Chemical Phosphorylation Reagents, Preparation, and Their Uses PTMS, PPP4C, CHAMP1 KMT2A 2135/4885KIF11 1762/4885HSD11B1 3917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.