SCHEMBL7924935

SCHEMBL7924935

C[Ti](C)(=[SiH2])(OC(=O)c1ccc(F)cc1)(OC(=O)c1ccc(F)cc1)(C1=CC=CC1)C1=CC=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.36
RAB9A P51151 4/20 0.36
MEN1 O00255 4/20 0.36
NPC1 O15118 3/20 0.36
MAPT P10636 3/20 0.36
MAPK1 P28482 2/20 0.36
HTT P42858 1/20 0.36
ATM Q13315 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
ADRB2 P07550 2/20 0.35
ADRB1 P08588 2/20 0.35
ADRB3 P13945 2/20 0.35
CYP1A2 P05177 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTGS1 P23219 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CASP3 P42574 1/20 0.33
TRPV1 Q8NER1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930807 0.86 TSHR (0.40) KMT2AMEN1MAPTMAPK1ADRB2
SCHEMBL7930965 0.81 MAPT (0.34) RAB9ANPC1MAPTCASP3SENP7
SCHEMBL7927389 0.76
SCHEMBL7924703 0.75 TERT (0.30)
SCHEMBL7924948 0.72
SCHEMBL7924606 0.72
SCHEMBL8158143 0.71 NPC1 (0.36) KMT2ARAB9AMEN1NPC1
SCHEMBL7925739 0.71 KMT2A (0.40) KMT2ARAB9AMEN1NPC1MAPK1
SCHEMBL7919426 0.71 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7928642 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed