SCHEMBL7925121

SCHEMBL7925121

C#CC(=O)O[Ti]1(OC(=O)C#C)C2C(=Cc3ccccc32)[Si](C)(C)C2=Cc3ccccc3C21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930983 0.83 POLB (0.35) LMNA
SCHEMBL7927402 0.80
SCHEMBL7925595 0.80 ALDH1A1 (0.32)
SCHEMBL7925634 0.80 LMNA (0.37) LMNA
SCHEMBL7930317 0.80 ELANE (0.31) LMNA
SCHEMBL7930339 0.80
SCHEMBL7930539 0.79 ELANE (0.31)
SCHEMBL7928108 0.79 THRB (0.32) LMNA
SCHEMBL7928240 0.78 ALDH1A1 (0.34) LMNA
SCHEMBL7930273 0.77 KCNN4 (0.41) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed