SCHEMBL7925209

SCHEMBL7925209

CC(COC(=O)C(C)(C)Cl)N=C=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18557894 0.86 PRKCA (0.44) PRKCA
SCHEMBL5175798 0.77
SCHEMBL16124234 0.76 TDP1 (0.38)
SCHEMBL26357271 0.75 TSHR (0.43) PRKCA
SCHEMBL28385506 0.73 NAAA (0.34)
SCHEMBL5175801 0.72 MAPT (0.34)
SCHEMBL648008 0.70 TSHR (0.58)
SCHEMBL814048 0.70 TSHR (0.58)
SCHEMBL28408522 0.70 ALDH1A1 (0.40)
SCHEMBL27901130 0.69 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6245935-B1 TREATING ISOCYANATOALKYL (METH)ACRYLATE CONTAINING A HYDROLYZABLE CHLORIDE WITH AN EPOXY GROUP-CONTAINING COMPOUND AND AN AMINE AND/OR AN IMIDAZOLE TO REDUCE CONTENT OF HYDROLYZABLE CHLORIDE IN ISOCYANATOALKYL (METH)ACRYLATE SHOWA DENKO KABUSHIKI KAISHA (JP) 2001-06-12 US disclosed
EP-0936214-A2 Method for producing isocyanatoalkyl (meth)acrylate Showa Denko Kabushiki Kaisha (JP) 1999-08-18 EP disclosed