SCHEMBL7925489

SCHEMBL7925489

CC(C)(C)C(=O)O[Ti]1(OC(=O)C(C)(C)C)C2C(=Cc3ccccc32)CC2=Cc3ccccc3C21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ELANE P08246 2/20 0.31
NAMPT P43490 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7931007 0.92 LMNA (0.33) LMNAMAPTNPSR1ELANENAMPT
SCHEMBL7927559 0.85 POLB (0.35) LMNA
SCHEMBL7928420 0.84 KCNN4 (0.39)
SCHEMBL7927323 0.81 ALDH1A1 (0.32) ELANE
SCHEMBL7930317 0.81 ELANE (0.31) LMNAMAPTNPSR1ELANE
SCHEMBL7930979 0.80 ALDH1A1 (0.37) LMNAMAPTNPSR1NAMPT
SCHEMBL7928090 0.80 ELANE (0.31) ELANE
SCHEMBL7927198 0.80 LMNA (0.36) LMNAMAPT
SCHEMBL7930339 0.78
SCHEMBL7930669 0.78 THRB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed