Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629949 | 0.84 | TAAR1 (0.38) | TAAR1IDO1GABRA1GABRB2TSHR | |
| SCHEMBL29466647 | 0.84 | TAAR1 (0.38) | TAAR1IDO1GABRA1GABRB2TSHR | |
| SCHEMBL18436948 | 0.82 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL12787109 | 0.78 | GABRA1 (0.54) | TAAR1IDO1GABRA1GABRB2TSHR | |
| SCHEMBL6525315 | 0.78 | APOBEC3G (0.35) | TAAR1IDO1GABRA1GABRB2TSHR | |
| SCHEMBL173876 | 0.78 | ALDH1A1 (0.36) | TAAR1IDO1GABRA1GABRB2TSHR | |
| SCHEMBL13905743 | 0.74 | — | — | |
| SCHEMBL7606121 | 0.71 | TAAR1 (0.35) | TAAR1IDO1GABRA1GABRB2 | |
| SCHEMBL1293367 | 0.70 | GABRA1 (0.48) | TAAR1IDO1GABRA1GABRB2TSHR | |
| SCHEMBL7886954 | 0.69 | TRPA1 (0.39) | TAAR1IDO1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |