SCHEMBL7926069

SCHEMBL7926069

O=C(Nc1ccccc1)NC1C(=O)N(CCN2CCOCC2)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 12/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8559712 0.92 CCKBR (0.66) CCKBR
SCHEMBL1388061 0.87 CCKBR (0.88) CCKBR
SCHEMBL1388262 0.85 CCKBR (0.85) CCKBR
SCHEMBL8867367 0.85 CCKBR (0.88) CCKBR
SCHEMBL8657907 0.84 CCKBR (1.00) CCKBR
SCHEMBL7375453 0.84 CCKBR (1.00) CCKBR
SCHEMBL7736909 0.84 CCKBR (0.81) CCKBR
SCHEMBL8866497 0.84 CCKBR (1.00) CCKBR
SCHEMBL8655654 0.83 CCKBR (1.00) CCKBR
SCHEMBL8556662 0.82 CCKBR (0.79) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785788-B1 USE OF CCK-B RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS GLAXO WELLCOME SPA (IT) 2001-12-12 EP claimed
EP-0785788-B1 USE OF CCK-B RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS GLAXO WELLCOME SPA (IT) 2001-12-12 EP disclosed
US-5716953-A MODIFIERS OF GASTRIN AND CHOLECYSTOKININS GLAXO WELLCOME S.P.A. (IT) 1998-02-10 US disclosed