Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790891 | 0.86 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRKDM4ERAB9A | |
| SCHEMBL12882119 | 0.85 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRKDM4ERAB9A | |
| SCHEMBL13545144 | 0.83 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2RAB9APKMHPGD | |
| SCHEMBL13074753 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KDM4ERAB9APKM | |
| Propionic Acid SCHEMBL7926726 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2RAB9APKMHPGD | |
| SCHEMBL11683297 | 0.79 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2RAB9ALMNAPKM | |
| SCHEMBL13543194 | 0.78 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TSHRKDM4ERAB9A | |
| SCHEMBL237337 | 0.77 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2TSHRRAB9ALMNA | |
| SCHEMBL7082818 | 0.77 | KMT2A (0.51) | ALDH1A1RAB9AKMT2ANPC1TP53 | |
| SCHEMBL6361865 | 0.76 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2TSHRRAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239152-B1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PHARMACIA & UPJOHN COMPANY | 2001-05-29 | — | — | US | disclosed |
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |