SCHEMBL237337

SCHEMBL237337

O=C(O)CNC(=O)c1ccco1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
SMN1; SMN2 Q16637 5/20 0.65
RAB9A P51151 4/20 0.65
NPC1 O15118 2/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
PKM P14618 1/20 0.64
HPGD P15428 1/20 0.62
CTDSP1 Q9GZU7 1/20 0.56
TSHR P16473 1/20 0.55
LMNA P02545 1/20 0.55
KMT2A Q03164 1/20 0.54
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL7926726 0.93 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
SCHEMBL4847926 0.84 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
SCHEMBL2969896 0.84 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
SCHEMBL13074753 0.84 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
SCHEMBL23014488 0.83 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
SCHEMBL11319921 0.82 SMN1; SMN2 (0.62) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
SCHEMBL8372267 0.82 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
SCHEMBL25885547 0.82 SMN1; SMN2 (0.70) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
SCHEMBL5123738 0.81 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1
Hippuric Acid SCHEMBL28149861 0.81 SMN1; SMN2 (0.55) ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOC DES PRODUITS NESTLE S A (CH) 2026-05-21 US claimed
US-12539288-B2 Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-02-03 US claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-20250341515-A1 METABOLOMIC BIOMARKERS FOR ACUTE KIDNEY INJURY, ASSAYS, COMPOSITIONS AND METHODS OF USE THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-11-06 US claimed
US-20250336540-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN PHARMACEUTICA NV (BE) 2025-10-30 US claimed
US-20250281438-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOCIETE DES PRODUITS NESTLE S.A. (CH) 2025-09-11 US claimed
WO-2025068213-A1 USE OF A MARKER SET FOR DETERMINING THE RISK OF HAVING OR DEVELOPING BLADDER CANCER NUMARES AG (DE) 2025-04-03 WO claimed
EP-4515242-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN Pharmaceutica NV (BE) 2025-03-05 EP claimed
CN-119165074-A NSCLC patient typing and third generation EGFR-TKI efficacy prediction model based on T790M mutation of plasma metabolite 中国医学科学院北京协和医院 2024-12-20 CN claimed
EP-4440563-A1 COMPOSITIONS AND METHODS USING AN AMINO ACID BLEND FOR PROVIDING A HEALTH BENEFIT IN AN ANIMAL Société des Produits Nestlé S.A. (CH) 2024-10-09 EP claimed
WO-1999005319-A9 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE INC (US) 1999-06-17 WO claimed
CN-1212019-A Methods and compositions for detecting ligand pair binding using non-fluorescent labels RAPIGENE INC (US) 1999-03-24 CN claimed
CN-1212021-A Method and compositions for determining sequence of nucleic acid molecules RAPIGENE INC (US) 1999-03-24 CN claimed
WO-1999005319-A2 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE, INC. (US) 1999-02-04 WO claimed
EP-0868535-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES Rapigene, Inc. (US) 1998-10-07 EP claimed
EP-0850320-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL DARWIN MOLECULAR CORPORATION (US) 1998-07-01 EP claimed
US-5686311-A ANALYZING FLUID SAMPLE THE CHILDREN'S MERCY HOSPITAL (US) 1997-11-11 US claimed
WO-1997027331-A9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES 1997-10-09 WO claimed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 WO claimed
WO-1997027327-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL RAPIGENE, INC. (US) 1997-07-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539288-B2 Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol LIPC, GGT1, TGM2 ALDH1A1 422/4885SMN1; SMN2 2843/4885RAB9A 3593/4885
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL LIPC, GGT1, TGM2 ALDH1A1 502/4885SMN1; SMN2 3433/4885RAB9A 3803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.