Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334443 | 0.81 | ALDH1A1 (0.55) | ALDH1A1GAAHTR2CTLR8PDE5A | |
| SCHEMBL6157353 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAHTR2CTLR8NFKB1 | |
| SCHEMBL4957802 | 0.78 | NFKB1 (0.46) | ALDH1A1GAAHTR2CTLR8NFKB1 | |
| SCHEMBL7927132 | 0.78 | ALDH1A1 (0.53) | ALDH1A1GAAHTR2CTLR8NFKB1 | |
| SCHEMBL1053375 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAAHTR2CTLR8NFKB1 | |
| SCHEMBL19121724 | 0.75 | HTR1B (0.53) | ALDH1A1GAANFKB1CYP1A2KDM4E | |
| SCHEMBL2761960 | 0.75 | ALDH1A1 (0.42) | ALDH1A1GAAHTR2CTLR8NFKB1 | |
| SCHEMBL677729 | 0.75 | ALDH1A1 (0.42) | ALDH1A1GAAHTR2CTLR8NFKB1 | |
| SCHEMBL7930783 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAACYP1A2KDM4ELMNA | |
| SCHEMBL1446334 | 0.74 | LMNA (0.61) | ALDH1A1GAAHTR2CCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661350-B1 | Quinizarin compound, method for production thereof, and use therefor | NIPPON CATALYTIC CHEM IND (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5817843-A | Quinizarin compound, method for production thereof, and use therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5608091-A | SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0661350-A1 | Quinizarin compound, method for production thereof, and use therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |