SCHEMBL7927152

SCHEMBL7927152

O=C1c2c(O)ccc(O)c2C(=O)c2c(F)c(Oc3ccccc3)c(Nc3c(Cl)cccc3Cl)c(F)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAPDH P04406 1/20 0.39
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA13 Q8N1Q1 1/20 0.37
MAOA P21397 1/20 0.36
STK39 Q9UEW8 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NSD2 O96028 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HKDC1 Q2TB90 1/20 0.34
TLR9 Q9NR96 1/20 0.34
EGFR P00533 1/20 0.34
PIM1 P11309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930030 0.85 CA12 (0.40) MEN1MAPTKMT2APOLBTDP1
SCHEMBL7921280 0.84 EGFR (0.45) MEN1MAPTKMT2AMAOAEGFR
SCHEMBL7933254 0.83 MAPT (0.39) MEN1MAPTKMT2ATDP1MAOA
SCHEMBL7921338 0.81 MAPT (0.37) MEN1MAPTKMT2ATDP1MAOA
SCHEMBL6652563 0.79 MAPT (0.36) MEN1MAPTKMT2APOLBTDP1
SCHEMBL7928355 0.78 ELANE (0.37) MEN1MAPTKMT2ACA12CA1
SCHEMBL8736473 0.78 PPARA (0.38) EGFRPIM1ACLY
SCHEMBL7921206 0.78 EGFR (0.41) EGFRPIM1PTGS2
SCHEMBL7921180 0.77 CXCR2 (0.44) MEN1MAPTKMT2APOLBGAPDH
SCHEMBL7930388 0.77 ELANE (0.37) MEN1KMT2AEGFRPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed