SCHEMBL792728

SCHEMBL792728

C=CC(=O)CCCOC(=O)CCCCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.41
MAPT P10636 1/20 0.41
DGKA P23743 1/20 0.40
LMNA P02545 2/20 0.39
NPC1 O15118 1/20 0.39
TSHR P16473 6/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 1/20 0.38
NFKB1 P19838 1/20 0.38
PMP22 Q01453 1/20 0.38
PAM P19021 2/20 0.37
HPGD P15428 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.34
DNM1 Q05193 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL542338 0.93 DGKA (0.45) MAPTDGKALMNATSHRALDH1A1
SCHEMBL9258220 0.91 TSHR (0.39) ABCC4MAPTDGKALMNANPC1
SCHEMBL8842750 0.87 TSHR (0.45) MAPTDGKATSHRALDH1A1CYP3A4
SCHEMBL3194001 0.84 LMNA (0.55) DGKALMNANPC1TSHRALDH1A1
SCHEMBL3210974 0.82 TSHR (0.57) DGKALMNATSHRALDH1A1NFKB1
SCHEMBL6283879 0.82 LMNA (0.58) ABCC4MAPTLMNATSHRALDH1A1
SCHEMBL29810451 0.82 TSHR (0.62) ABCC4MAPTDGKALMNANPC1
SCHEMBL29810452 0.82 TSHR (0.57) ABCC4MAPTDGKALMNANPC1
SCHEMBL19934811 0.81 TSHR (0.66) ABCC4MAPTDGKALMNANPC1
SCHEMBL19934818 0.81 TSHR (0.66) ABCC4MAPTDGKALMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3935117-A1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2022-01-12 EP disclosed
EP-2970718-A2 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2016-01-20 EP disclosed
WO-2014140804-A2 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2014-09-18 WO disclosed
EP-2616520-A1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS Henkel Ireland Limited (DE) 2013-07-24 EP disclosed
WO-2012035112-A1 TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS LOCTITE (R&D) LIMITED (IE) 2012-03-22 WO disclosed