SCHEMBL7927327

SCHEMBL7927327

O=C1c2ccc(F)cc2C(=O)c2c(O)ccc(O)c21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.57
KMT2A Q03164 6/20 0.57
MAPT P10636 6/20 0.57
MAOA P21397 6/20 0.57
HPGD P15428 4/20 0.57
ALDH1A1 P00352 4/20 0.57
MAPK1 P28482 4/20 0.57
TDP1 Q9NUW8 4/20 0.57
APEX1 P27695 3/20 0.57
KDM4E B2RXH2 3/20 0.57
CYP3A4 P08684 3/20 0.57
ALOX15 P16050 3/20 0.57
RECQL P46063 3/20 0.57
HSD17B10 Q99714 3/20 0.57
BRCA1 P38398 2/20 0.57
THRB P10828 2/20 0.57
CSNK2A2 P19784 2/20 0.57
CSNK2B P67870 2/20 0.57
CSNK2A1 P68400 2/20 0.57
CSNK2A3 Q8NEV1 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11142031 0.81 APAF1 (0.52) MAOAALDH1A1KDM4ECYP3A4TTR
SCHEMBL9328908 0.80 CA1 (0.52) MEN1KMT2AMAOAALDH1A1MAPK1
SCHEMBL28682656 0.80 MEN1 (0.49) MEN1KMT2AMAPTMAOAHPGD
SCHEMBL6906327 0.79 TTR (0.72) MEN1KMT2AMAPTMAOAHPGD
SCHEMBL9297198 0.78 MEN1 (0.47) MEN1KMT2AMAPTMAOAHPGD
SCHEMBL9811010 0.76 CA1 (0.48) MAPTMAOAALDH1A1MAPK1TDP1
SCHEMBL25212160 0.76 MCL1 (0.71) MEN1KMT2AMAPTMAOAHPGD
SCHEMBL375798 0.76 LCK (0.67) MEN1KMT2AMAPTMAOAHPGD
SCHEMBL6659611 0.76 ALDH1A1 (0.59) MEN1KMT2AMAPTMAOAHPGD
SCHEMBL10701454 0.76 HSP90AA1 (0.65) MEN1KMT2AMAPTMAOAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed