Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921789 | 0.91 | CCR3 (0.45) | HTR2ACCR3MEN1KMT2AMGLL | |
| SCHEMBL7921581 | 0.89 | KCNH2 (0.45) | HTR2ACCR3MEN1KMT2AMGLL | |
| SCHEMBL7921870 | 0.89 | TACR1 (0.47) | HTR2ACCR3MEN1KMT2AMGLL | |
| SCHEMBL7927354 | 0.88 | KCNH2 (0.49) | HTR2ACCR3MEN1KMT2AMGLL | |
| SCHEMBL7924050 | 0.85 | MEN1 (0.50) | CCR3MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7927130 | 0.84 | MEN1 (0.54) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL7927342 | 0.83 | LMNA (0.49) | HTR2ACCR3MEN1KMT2AMGLL | |
| SCHEMBL6139831 | 0.81 | LMNA (0.56) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL7924041 | 0.80 | ATM (0.47) | HTR2AMEN1KMT2ALMNAGAA | |
| SCHEMBL7915448 | 0.79 | KDM4E (0.46) | RAB9AMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |