Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921581 | 0.93 | KCNH2 (0.45) | CCR3KMT2AMEN1KCNH2ALDH1A1 | |
| SCHEMBL7927354 | 0.92 | KCNH2 (0.49) | CCR3KMT2AMEN1KCNH2ALDH1A1 | |
| SCHEMBL7927367 | 0.91 | RAB9A (0.46) | CCR3KMT2AMEN1ALDH1A1MGLL | |
| SCHEMBL7921870 | 0.90 | TACR1 (0.47) | CCR3KMT2AMEN1KCNH2ALDH1A1 | |
| SCHEMBL7927342 | 0.85 | LMNA (0.49) | CCR3KMT2AMEN1KCNH2ALDH1A1 | |
| SCHEMBL7927349 | 0.82 | MEN1 (0.50) | CCR3KMT2AMEN1ALDH1A1 | |
| SCHEMBL7923414 | 0.81 | MEN1 (0.54) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL7921573 | 0.80 | LMNA (0.58) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL7915427 | 0.79 | NPSR1 (0.47) | KMT2AMEN1KCNH2ALDH1A1MAPT | |
| SCHEMBL7915440 | 0.77 | DRD2 (0.51) | KMT2AMEN1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |