Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.59 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103615 | 1.00 | NOD1 (0.59) | NOD1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27892995 | 1.00 | NOD1 (0.59) | NOD1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4217551 | 1.00 | NOD1 (0.59) | NOD1GABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL7349143 | 0.98 | NOD1 (0.58) | NOD1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10888261 | 0.94 | NOD1 (0.54) | NOD1GABRPGABRDGABRA1GABRB1 | |
| Trifluoroacetic Acid SCHEMBL25386515 | 0.91 | NOD1 (0.52) | NOD1GABRPGABRDGABRA1GABRB1 | |
| Trifluoroacetic Acid SCHEMBL11191547 | 0.91 | NOD1 (0.52) | NOD1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17888187 | 0.88 | NOD1 (0.49) | NOD1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1270356 | 0.87 | FOLH1 (0.60) | NOD1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2490631 | 0.87 | FOLH1 (0.60) | NOD1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063613-A | MUTANT STAPHYLOCOCCUS AUREUS CAUSED BY INSERTION OF TRANSPOSON TN551; CAUSES INCORPORATION OF PARTIALLY BLOCKED MUROPEPTIDE PRECURSORS INTO CELL WALL; FOR SCREENING DRUGS THAT CAN REVERSE, INHIBIT OR REDUCE BACTERIAL RESISTANCE | THE ROCKEFELLER UNIVERSITY (US) | 2000-05-16 | — | — | US | claimed |
| WO-1995016039-A1 | AUXILIARY GENES AND PROTEINS OF METHICILLIN RESISTANT BACTERIA AND ANTAGONISTS THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 1995-06-15 | — | — | WO | claimed |
| CN-119604618-A | Epstein-Barr virus vaccine | 巴法里安诺迪克有限公司 | 2025-03-11 | — | — | CN | disclosed |
| US-11925643-B2 | Toll-like receptor 4 (TLR4) inhibitors and use thereof | MOR RESEARCH APPLICATIONS LTD. (IL) | 2024-03-12 | — | — | US | disclosed |
| CN-116396940-A | Hematopoietic stem progenitor cells, preparation method and application thereof | 北京干细胞与再生医学研究院 | 2023-07-07 | — | — | CN | disclosed |
| CN-108884439-A | For cultivating method, culture medium and the product of embryo | 阿德莱德大学 | 2018-11-23 | — | — | CN | disclosed |
| US-8278090-B1 | Heterotrophic cultivation of hydrocarbon-producing microalgae | SOLAZYME, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-6251647-B1 | NUCLEOTIDE AND AMINO ACID SEQUENCES; DRUG SCREENING OF BACTERICIDES FOR STAPHYLOCOCCUS INFECTIONS | THE ROCKEFELLER UNIVERSITY | 2001-06-26 | — | — | US | disclosed |
| US-6136587-A | ANTIBIOTIC RESISTANT STAPHYLOCOCCUS STRAIN HAVING A MUTATION IN A GENE WHICH LEADS TO AMPLIFIED SENSITIVITY TO ANTIBIOTICS; FOR THE TREATMENT OF MICROORGANISM INFECTION | THE ROCKEFELLER UNIVERSITY (US) | 2000-10-24 | — | — | US | disclosed |
| US-6063613-A | MUTANT STAPHYLOCOCCUS AUREUS CAUSED BY INSERTION OF TRANSPOSON TN551; CAUSES INCORPORATION OF PARTIALLY BLOCKED MUROPEPTIDE PRECURSORS INTO CELL WALL; FOR SCREENING DRUGS THAT CAN REVERSE, INHIBIT OR REDUCE BACTERIAL RESISTANCE | THE ROCKEFELLER UNIVERSITY (US) | 2000-05-16 | — | — | US | disclosed |
| US-6013507-A | NUCLEIC ACID SEQUENCES WHICH CODE FOR A PROTEIN ASSOCIATED WITH ANTIBIOTIC RESISTANCE IN STAPHYLOCUCCUS; FOR THE DETECTION OF COMPOUNDS THAT CAN REVERSE ANTIBIOTIC RESISTANCE | THE ROCKEFELLER UNIVERSITY (US) | 2000-01-11 | — | — | US | disclosed |
| US-6008333-A | Preparation of glucosaminyl muramic acid derivatives | ENDOREX CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0873345-A1 | PREPARATION OF GLUCOSAMINYL MURAMIC ACID DERIVATIVES | Endorex Corporation (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5750665-A | Preparation of glucosaminyl muramic acid derivatives | ENDOREX CORPORATION | 1998-05-12 | — | — | US | disclosed |
| WO-1997012894-A1 | PREPARATION OF GLUCOSAMINYL MURAMIC ACID DERIVATIVES | ENDOREX CORPORATION (US) | 1997-04-10 | — | — | WO | disclosed |
| WO-1995016039-A1 | AUXILIARY GENES AND PROTEINS OF METHICILLIN RESISTANT BACTERIA AND ANTAGONISTS THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 1995-06-15 | — | — | WO | disclosed |
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | disclosed |
| US-5110798-A | Immunomodulators for bone marrow transplants | CO PHARMA CORPORATION S.R.L. (IT) | 1992-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11925643-B2 | Toll-like receptor 4 (TLR4) inhibitors and use thereof | TLR4, TLR1, TLR3 | NOD1 9/4885GABRP 2241/4885GABRD 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.