SCHEMBL2490631

SCHEMBL2490631

C[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 8/20 0.60
NAALAD2 Q9Y3Q0 3/20 0.60
RIMKLA Q8IXN7 1/20 0.60
NOD1 Q9Y239 1/20 0.57
GABRP O00591 2/20 0.50
GABRD O14764 2/20 0.50
GABRA1 P14867 2/20 0.50
GABRB1 P18505 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50
GABRA4 P48169 2/20 0.50
GABRE P78334 2/20 0.50
GABRA6 Q16445 2/20 0.50
GABRG1 Q8N1C3 2/20 0.50
GABRG3 Q99928 2/20 0.50
GABRQ Q9UN88 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11188341 1.00 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL7937311 1.00 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL29959406 1.00 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL7762097 1.00 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL1270356 1.00 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL23044064 1.00 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
Hydrochloric Acid SCHEMBL8728073 0.98 FOLH1 (0.58) FOLH1NAALAD2RIMKLANOD1GABRP
Hydrochloric Acid SCHEMBL11283847 0.98 FOLH1 (0.58) FOLH1NAALAD2RIMKLANOD1GABRP
Hydrochloric Acid SCHEMBL8728071 0.98 FOLH1 (0.58) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL28727840 0.96 FOLH1 (0.56) FOLH1NAALAD2RIMKLANOD1GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 410 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504166-B1 TOPICAL FORMULATION FOR USE IN THE TREATMENT OR PREVENTION OF ITCHY DRY SKIN MC2 THERAPEUTICS LTD (GB) 2026-04-29 EP claimed
EP-4695413-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2026-02-18 EP claimed
US-20260034090-A1 CANNABINOID PRODRUG COMPOUNDS FIRSTLIGHT PHARMACEUTICALS LLC (US) 2026-02-05 US claimed
US-20250263437-A1 POLYPEPTIDE FOR REPAIRING SKIN WOUND OR MUCOSAL INJURY, AND APPLICATION THEREOF SICHUAN GOODDOCTOR PANXI PHARMACEUTICAL CO., LTD. (CN) 2025-08-21 US claimed
US-12377110-B2 Fospropofol methods and compositions EPALEX CORPORATION (US) 2025-08-05 US claimed
US-20250222063-A1 TOPICAL FORMULATION FOR USE IN THE TREATMENT OR PREVENTION OF DRY ITCHY SKIN MC2 THERAPEUTICS LTD (GB) 2025-07-10 US claimed
CN-120084911-A Method for measuring alanyl glutamine related substances 苏州科伦药物研究有限公司 2025-06-03 CN claimed
CN-113933403-B Method for measuring alanyl glutamine related substances 苏州科伦药物研究有限公司 2025-04-25 CN claimed
EP-4504166-A1 TOPICAL FORMULATION FOR USE IN THE TREATMENT OR PREVENTION OF ITCHY DRY SKIN MC2 Therapeutics Limited (GB) 2025-02-12 EP claimed
CN-119224161-A Method for detecting various dipeptides in rumen fluid of ruminant 中国科学院亚热带农业生态研究所 2024-12-31 CN claimed
CN-111296222-A Transplanting process for big trees 华绿建设有限公司 2020-06-19 CN claimed
CN-108514529-A A kind of extracting method and application thereof of skin-lightening cosmetic Chinese medical extract 张言聚 2018-09-11 CN claimed
WO-2018065279-A1 METHOD OF REDUCING MALODOUR UNILEVER PLC (GB) 2018-04-12 WO claimed
US-8815800-B2 Moisturizing composition comprising an aminopeptide mixture CONOPCO, INC. (US) 2014-08-26 US claimed
CN-1602190-A Use of glutamate, glutamate derivatives or metabolites, glutamate analogues or mixtures thereof for the manufacture of a composition for the treatment of osteoporosis ESSENTYS AB (SE) 2005-03-30 CN claimed
US-20040259766-A1 Bone disorders; administering to mammals, humans, poultry PROTISTA CORPORATION AB (SE) 2004-12-23 US claimed
EP-1446112-A1 USE OF GLUTAMATE, GLUTAMATE DERIVATIVES OR METABOLITES, GLUTAMATE ANALOGUES OR MIXTURES THEREOF FOR THE MANUFACTURE OF A COMPOSITION FOR THE TREATMENT OF OSTEOPOROSIS Essentys AB (SE) 2004-08-18 EP claimed
WO-2003043626-A1 USE OF GLUTAMATE, GLUTAMATE DERIVATIVES OR METABOLITES, GLUTAMATE ANALOGUES OR MIXTURES THEREOF FOR THE MANUFACTURE OF A COMPOSITION FOR THE TREATMENT OF OSTEOPOROSIS ESSENTYS AB (SE) 2003-05-30 WO claimed
US-6063613-A MUTANT STAPHYLOCOCCUS AUREUS CAUSED BY INSERTION OF TRANSPOSON TN551; CAUSES INCORPORATION OF PARTIALLY BLOCKED MUROPEPTIDE PRECURSORS INTO CELL WALL; FOR SCREENING DRUGS THAT CAN REVERSE, INHIBIT OR REDUCE BACTERIAL RESISTANCE THE ROCKEFELLER UNIVERSITY (US) 2000-05-16 US claimed
WO-1995016039-A1 AUXILIARY GENES AND PROTEINS OF METHICILLIN RESISTANT BACTERIA AND ANTAGONISTS THEREOF THE ROCKEFELLER UNIVERSITY (US) 1995-06-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250222063-A1 TOPICAL FORMULATION FOR USE IN THE TREATMENT OR PREVENTION OF DRY ITCHY SKIN SLC14A1, ITCH, HNMT FOLH1 1060/4885NAALAD2 204/4885RIMKLA 1980/4885
US-20260034090-A1 CANNABINOID PRODRUG COMPOUNDS CNR1, CNR2, FAAH FOLH1 941/4885NAALAD2 2634/4885RIMKLA 567/4885
US-12377110-B2 Fospropofol methods and compositions FOS, FOSB, PFAS FOLH1 387/4885NAALAD2 4066/4885RIMKLA 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.