SCHEMBL7927562

SCHEMBL7927562

COC(=O)C1(C)CCO[CH]O1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 1/20 0.33
PKM P14618 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929094 0.82 MEN1 (0.33) NPSR1LMNAMEN1KMT2A
SCHEMBL7921717 0.80 OPRM1 (0.35) MEN1KMT2A
SCHEMBL18789234 0.72 NPSR1 (0.32) NPSR1CYP3A4MEN1KMT2A
SCHEMBL11636681 0.69 CYP3A4 (0.33) NPSR1CYP3A4CYP2C9PKMCYP2C19
SCHEMBL24780247 0.68 NPSR1 (0.39) NPSR1LMNACYP3A4CYP2C9PKM
SCHEMBL2185550 0.68 NPSR1 (0.39) NPSR1LMNACYP3A4CYP2C9PKM
SCHEMBL7563288 0.68 SMN1; SMN2 (0.34) NPSR1CYP3A4CYP2C9PKMCYP2C19
SCHEMBL757258 0.68
SCHEMBL2121481 0.68
SCHEMBL18806638 0.67 NPSR1 (0.42) NPSR1LMNACYP3A4CYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031865-A1 Substituted 3-phenyluracils KLINTZ RALF (DE) 2001-10-18 US disclosed
US-6239074-B1 HERBICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-05-29 US disclosed
EP-0604491-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF Aktiengesellschaft (DE) 1994-07-06 EP disclosed
WO-1993006090-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031865-A1 Substituted 3-phenyluracils CCR1, CCR6, CCR3 NPSR1 2275/4885LMNA 1409/4885CYP3A4 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.