Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108583 | 0.82 | PSEN1 (0.31) | — | |
| SCHEMBL11636681 | 0.81 | CYP3A4 (0.33) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL8108521 | 0.81 | PSEN1 (0.30) | — | |
| SCHEMBL8106280 | 0.79 | LMNA (0.42) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL7561746 | 0.69 | — | — | |
| SCHEMBL7927562 | 0.68 | NPSR1 (0.33) | MEN1KMT2ACYP3A4CYP2C9PKM | |
| SCHEMBL18789234 | 0.67 | NPSR1 (0.32) | MEN1KMT2ACYP3A4NPSR1 | |
| SCHEMBL18789245 | 0.66 | SMN1; SMN2 (0.33) | SMN1; SMN2MEN1KMT2ACYP3A4NPSR1 | |
| SCHEMBL757258 | 0.63 | — | — | |
| SCHEMBL2121481 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013652-B1 | Process for preparation of substituted chromanderivatives | BASF AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-1013652-A2 | Process for preparation of substituted chromanderivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |