Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966052 | 1.00 | TDP1 (0.46) | TDP1L3MBTL1ATMCYP3A4CYP2C9 | |
| SCHEMBL19998347 | 0.93 | MT-CO2 (0.46) | TDP1L3MBTL1ATMCYP3A4CYP2C9 | |
| SCHEMBL19998349 | 0.93 | MT-CO2 (0.46) | TDP1L3MBTL1ATMCYP3A4CYP2C9 | |
| SCHEMBL504005 | 0.90 | L3MBTL1 (0.55) | TDP1L3MBTL1ATMCYP3A4CYP2C9 | |
| SCHEMBL22579290 | 0.89 | MT-CO2 (0.43) | TDP1L3MBTL1ATMCYP3A4ALDH1A1 | |
| SCHEMBL21795248 | 0.88 | MT-CO2 (0.39) | TDP1L3MBTL1ATMCYP3A4CYP2C9 | |
| SCHEMBL13148775 | 0.87 | TDP1 (0.49) | TDP1L3MBTL1ATMCYP3A4CYP2C9 | |
| SCHEMBL13148766 | 0.87 | TDP1 (0.49) | TDP1L3MBTL1ATMCYP3A4CYP2C9 | |
| SCHEMBL13148723 | 0.87 | TDP1 (0.49) | TDP1L3MBTL1ATMCYP3A4CYP2C9 | |
| SCHEMBL23951598 | 0.86 | ATM (0.42) | TDP1L3MBTL1ATMGSK3BMT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235871-B1 | Synthesis of oligoarylamines, and uses and reagents related thereto | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-22 | — | — | US | disclosed |