Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL792376 | 0.95 | MTNR1A (0.41) | MTNR1AMTNR1BSCN9APRKCAMMP12 | |
| SCHEMBL793024 | 0.87 | PRKCA (0.34) | MTNR1AMTNR1BSCN9APRKCAMMP12 | |
| SCHEMBL793064 | 0.83 | SCN9A (0.33) | SCN9APRKCAMMP12 | |
| SCHEMBL792822 | 0.83 | PRKCA (0.44) | SCN9APRKCAMMP12 | |
| SCHEMBL792554 | 0.83 | SCN9A (0.35) | SCN9APRKCAMMP12 | |
| SCHEMBL792720 | 0.80 | PRKCA (0.45) | SCN9APRKCAMMP12 | |
| SCHEMBL793115 | 0.80 | PRKCA (0.34) | SCN9APRKCAMMP12 | |
| SCHEMBL793019 | 0.80 | MTNR1A (0.38) | MTNR1AMTNR1BSCN9APRKCAMMP12 | |
| SCHEMBL772130 | 0.79 | PRKCA (0.53) | MTNR1AMTNR1BSCN9APRKCAMMP12 | |
| SCHEMBL772587 | 0.78 | SCN9A (0.47) | MTNR1AMTNR1BSCN9APRKCAMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | POLI, TERT, ZC3HAV1 | MTNR1A 4311/4885MTNR1B 4142/4885SCN9A 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.