SCHEMBL7928255

SCHEMBL7928255

Cc1cccc(Cl)c1Nc1ccc2c(c1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAOA P21397 1/20 0.41
STK10 O94804 2/20 0.39
GSK3B P49841 2/20 0.39
SLK Q9H2G2 2/20 0.39
CXCR2 P25025 1/20 0.39
DHODH Q02127 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.39
PTGS2 P35354 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PTPRC P08575 1/20 0.38
P2RY2 P41231 1/20 0.38
P2RY1 P47900 1/20 0.38
P2RY4 P51582 1/20 0.38
P2RY6 Q15077 1/20 0.38
P2RY12 Q9H244 1/20 0.38
LMNA P02545 2/20 0.37
MAPK1 P28482 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933233 0.91 DHODH (0.47) MAPTMEN1KMT2AMAOACXCR2
SCHEMBL7929799 0.91 MEN1 (0.46) MAPTMEN1KMT2AMAOASTK10
SCHEMBL7928338 0.83 MAPT (0.47) MAPTMEN1KMT2AMAOACXCR2
SCHEMBL7929854 0.82 POLB (0.50) MAPTMEN1KMT2AGSK3BCXCR2
SCHEMBL7933258 0.78 MEN1 (0.44) MAPTMEN1KMT2AMAOASMN1; SMN2
SCHEMBL7921179 0.78 MEN1 (0.44) MAPTMEN1KMT2AMAOASMN1; SMN2
SCHEMBL7921156 0.77 MEN1 (0.42) MAPTMEN1KMT2AMAOASMN1; SMN2
SCHEMBL7929769 0.76 PTGS2 (0.41) CXCR2DHODHPTGS2CHRNA7MAPK14
SCHEMBL8394314 0.75 ITGA1 (0.49) MAPTMEN1KMT2AMAOASTK10
SCHEMBL29502802 0.75 ITGA1 (0.49) MAPTMEN1KMT2AMAOASTK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed